ASO Author Reflection: Viruses, the Lung, and Thoracic Neoplasms: Breaking Bad

Radiotherapy in thoracic neoplasms.

Coming Good and Breaking Bad

Stories move us emotionally by physically moving their protagonists, from place to place or from state to state. The most psychologically compelling stories are stories of change, in which characters learn and evolve as they fulfil their dreams or become what they most despise. Character-driven stories must do more than maneouver their protagonists as game pieces on a board, but move them along...

Breaking bad news.

Breaking Bad News

Even the most skilled physician knows that conveying bad news to a patient or family can be one of the most arduous aspects of health care. Historically, breaking bad news is a skill that has generally been under-emphasized in training programmes. Critical care physicians are commonly faced with the difficult task of breaking bad news, often in dramatic, emotional and unexpected situations. Bre...

The impact of spironolactone on the lung injury induced by concomitant trastuzumab and thoracic radiotherapy

Background: To evaluate impact of spironolactone (S) on pulmonary toxicity of concomitant use of thoracic radiotherapy (RT) and trastuzumab (T).  Materials and Methods: Eighty rats were divided into eight groups: group (G) 1 was control group; G2, G3 and G4 were RT, S and T groups; G5, G6, G7 and G8 were RT+T, T+S, RT+S and RT+T+S groups respectively. Rats were sacrificed at 6 hour, 21 and 100 ...